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Fundamentals of Bioinformatics

Biological Databases and file formats

Biological Databases and file formats

Introduction to Computational Biology and Bioinformatics
Computational Biology Vs Bioinformatics
Introduction to Ubuntu Linux
Basic operating commands of Linux
Applications of Bioinformatics

Biological Databases and file formats

Biological Databases and file formats

Biological Databases and file formats

Introduction to database
Types of databases
Database management system
Biological databases and types
Database file formats
Data retrieval system
Keyword searching with logical operators

Similarity search algorithms

Biological Databases and file formats

Molecular phylogeny and applications

The need for Database Searching
Searching algorithm types
Basic Local Alignment Search Tool (BLAST)
FASTA (FAST All)
Application of searching tools

Molecular phylogeny and applications

Molecular dynamics simulation and applications

Molecular phylogeny and applications

Basics of molecular phylogenetics
Phylogenetic tree construction methods
Distance-based methods
Character-based methods
Statistical evaluation of trees
Tools like CLUSTAL, PHYLIP, MUSCLE
Software like MEGA, BioEdit

Macro molecular structure and modelling

Molecular dynamics simulation and applications

Molecular dynamics simulation and applications

Amino acid residue types and classification
The hierarchy of protein structure
The secondary structural elements
Molecular modelling types (homology, threading and ab initio)
Molecular modelling programs

Molecular dynamics simulation and applications

Molecular dynamics simulation and applications

Molecular dynamics simulation and applications

Molecular Dynamics Simulation Initiative
The concept of different molecular systems
The molecular dynamics algorithm
Setting up, running and analyzing simulation
Applications (case studies)

Virtual screening and docking

Next generation sequencing analysis

Next generation sequencing analysis

Selection of compounds from chemical databases
Filtering of lead-like compounds
Generation of 3D structures
Selection of representative chemical structure
Assembling list of compounds for virtual screening
Molecular docking

Next generation sequencing analysis

Next generation sequencing analysis

Next generation sequencing analysis

Basic concepts of Next Generation Sequencing
Types of sequencing methods
Types of NGS platforms
Preparation of library
Generation of potential clusters
The sequencing
Final alignment and data analysis

Systems biology and networks

Next generation sequencing analysis

Systems biology and networks

Basic concepts of systems biology
The graph theory and methods of centrality calculations
Generation of PPI network with information from different database
Network visualizations and analysis
Significances of different networks in biomedical research